Basic Concepts in Medicinal Chemistry

Basic Concepts in Medicinal Chemistry
Author :
Publisher : ASHP
Total Pages : 405
Release :
ISBN-10 : 9781585283644
ISBN-13 : 1585283649
Rating : 4/5 (44 Downloads)

Book Synopsis Basic Concepts in Medicinal Chemistry by : Marc Harrold

Download or read book Basic Concepts in Medicinal Chemistry written by Marc Harrold and published by ASHP. This book was released on 2013-01-18 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.


Basic Concepts in Medicinal Chemistry Related Books

Basic Concepts in Medicinal Chemistry
Language: en
Pages: 405
Authors: Marc Harrold
Categories: Medical
Type: BOOK - Published: 2013-01-18 - Publisher: ASHP

DOWNLOAD EBOOK

Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental
Basic Concepts in Medicinal Chemistry
Language: en
Pages: 606
Authors: Marc W. Harrold
Categories: Pharmaceutical chemistry
Type: BOOK - Published: 2018 - Publisher:

DOWNLOAD EBOOK

"This updated and expanded edition of the popular textbook, Basic Concepts in Medicinal Chemistry, has been enhanced with new subject material, numerous self-as
Basic Concepts in Medicinal Chemistry
Language: en
Pages: 0
Authors: Marc W. Harrold
Categories: Drug interactions
Type: BOOK - Published: 2018 - Publisher:

DOWNLOAD EBOOK

Functional group characteristics and roles -- Identifying acidic and basic functional groups -- Solving pH and pKa problems -- Salts and solubility -- Drug bind
Organic Chemistry Concepts and Applications for Medicinal Chemistry
Language: en
Pages: 219
Authors: Joseph E. Rice
Categories: Science
Type: BOOK - Published: 2014-04-14 - Publisher: Academic Press

DOWNLOAD EBOOK

Organic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding an
The Practice of Medicinal Chemistry
Language: en
Pages: 903
Authors: Camille Georges Wermuth
Categories: Science
Type: BOOK - Published: 2015-07-01 - Publisher: Elsevier

DOWNLOAD EBOOK

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and ch