Download or read book The Construction of Analogy-Based Research Programs written by Rebecca Mertens and published by transcript Verlag. This book was released on 2019-04-30 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the German chemist Emil Fischer presented his lock-and-key hypothesis in 1899, his analogy to describe the molecular relationship between enzymes and substrates quickly gained vast influence and provided future generations of scientists with a tool to investigate the relation between chemical structure and biological specificity. Rebecca Mertens explains the appeal of the lock-and-key analogy by its role in model building and in the construction of long-term, cross-generational research programs. She argues that a crucial feature of these research programs, namely ascertaining the continuity of core ideas and concepts, is provided by a certain way of analogy-based modelling.